The DRD1 Polyclonal Antibody (CAB2893) is a crucial tool for researchers studying the dopamine receptor D1 (DRD1), a key player in the regulation of neurotransmission and behavior. This antibody, produced through immunization of rabbits, shows high specificity and reactivity with human samples, making it ideal for use in Western blot applications.DRD1, also known as the D1 receptor, is involved in mediating the effects of dopamine in the brain and is associated with various neurological disorders, including schizophrenia and Parkinson's disease. By targeting the DRD1 protein, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.
With its ability to detect and analyze DRD1 in different cell types, the DRD1 Polyclonal Antibody is a valuable tool for studies in neuroscience, pharmacology, and drug development. By understanding the role of DRD1 in neurotransmission and behavior, researchers can further our knowledge of brain function and potentially pave the way for the development of novel treatments for neurological disorders.
Product Name:
DRD1 Rabbit Polyclonal Antibody
SKU:
CAB2893
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1).
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
Purification Method:
Affinity purification
Gene ID:
1812
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat brain, using DRD1 antibody (CAB2893) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.2s.
