DRAP1 Rabbit Polyclonal Antibody (CAB17616)
- SKU:
- CAB17616
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | DRAP1 Rabbit Polyclonal Antibody |
SKU: | CAB17616 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human DRAP1 (NP_006433.2). |
Sequence: | LKKA CQVT QSRN AKTM TTSH LKQC IELE QQFD FLKD LVAS VPDM QGDG EDNH MDGD KGAR RGRK PGSG GRKN GGMG TKSK DKKL SGTD SEQE DESE DTDT D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NC2-alpha; DRAP1 |
Positive Sample: | U-87MG,Jurkat,293T,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | nucleus |
Calculated MW: | 22kDa |
Observed MW: | 32-38kDa |
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.
Purification Method: | Affinity purification |
Gene ID: | 10589 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |