DR1 Rabbit Polyclonal Antibody (CAB13298)
- SKU:
- CAB13298
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | DR1 Rabbit Polyclonal Antibody |
SKU: | CAB13298 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-176 of human DR1 (NP_001929.1). |
Sequence: | MASS SGND DDLT IPRA AINK MIKE TLPN VRVA NDAR ELVV NCCT EFIH LISS EANE ICNK SEKK TISP EHVI QALE SLGF GSYI SEVK EVLQ ECKT VALK RRKA SSRL ENLG IPEE ELLR QQQE LFAK ARQQ QAEL AQQE WLQM QQAA QQAQ LAAA SASA SNQA GSSQ DEED DDDI |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NC2; NC2B; NCB2; NC2-BETA; DR1 |
Positive Sample: | Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 19kDa |
Observed MW: | 19kDa |
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
Purification Method: | Affinity purification |
Gene ID: | 1810 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |