The DPYSL3 Polyclonal Antibody (CAB12280) is a valuable tool for researchers studying DPYSL3, a protein involved in neuronal development and function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DPYSL3 protein, this antibody allows for the detection and analysis of DPYSL3 in various cell types, making it an excellent choice for neuroscience and neurobiology research.DPYSL3, also known as collapsin response mediator protein 4 (CRMP4), plays a crucial role in axon outgrowth and guidance during neuronal development.
Its involvement in neuronal signaling pathways makes it a compelling target for investigating neurological disorders and conditions such as Alzheimer's disease, Parkinson's disease, and traumatic brain injuries. Understanding the function of DPYSL3 is essential for developing new therapeutic strategies aimed at treating these complex neurological conditions and improving patient outcomes.
Product Name:
DPYSL3 Rabbit Polyclonal Antibody
SKU:
CAB12280
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 440-520 of human DPYSL3 (NP_001378.1).
Enables filamin binding activity. Predicted to be involved in several processes, including actin filament organization; regulation of plasma membrane bounded cell projection organization; and response to axon injury. Predicted to act upstream of or within nervous system development. Predicted to be located in several cellular components, including cell body; growth cone; and lamellipodium. Predicted to be part of filamentous actin. Predicted to be active in synapse. Predicted to colocalize with exocytic vesicle.
Purification Method:
Affinity purification
Gene ID:
1809
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DPYSL3 Rabbit pAb (CAB12280) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
