DPYD Rabbit Polyclonal Antibody (CAB1620)
- SKU:
- CAB1620
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DPYD Rabbit Polyclonal Antibody |
SKU: | CAB1620 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_000101.2). |
Sequence: | MAPV LSKD SADI ESIL ALNP RTQT HATL CSTS AKKL DKKH WKRN PDKN CFNC EKLE NNFD DIKH TTLG ERGA LREA MRCL KCAD APCQ KSCP TNLD IKSF ITSI ANKN YYGA AKMI FSDN PLGL TCGM VCPT SDLC VGGC NLYA TEEG PINI GGLQ QFAT ETLI LAFS LMNH L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DHP; DPD; DYPD; DHPDHASE; DPYD |
Positive Sample: | THP-1,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 111kDa |
Observed MW: | 112kDa |
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1806 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |