DPPA4 Rabbit Polyclonal Antibody (CAB13724)
- SKU:
- CAB13724
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | DPPA4 Rabbit Polyclonal Antibody |
SKU: | CAB13724 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-304 of human DPPA4 (NP_060659.3). |
Sequence: | KGKE WTST EKSR EEDQ QASN QPNS IALP GTSA KRTK EKMS IKGS KVLC PKKK AEHT DNPR PQKK IPIP PLPS KLPP VNLI HRDI LRAW CQQL KLSS KGQK LDAY KRLC AFAY PNQK DFPS TAKE AKIR KSLQ KKLK VEKG ETSL QSSE THPP EVAL PPVG EPPA LENS TALL EGVN TVVV TTSA PEAL LASW ARIS ARAR TPEA VESP QEAS GVRW CVVH GKSL PADT DGWV HLQF HAGQ AWVP EKQE GRVS ALFL LPAS NFPP PHLE DNML CPKC VHRN KVLI KSLQ WE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | 2410091M23Rik; DPPA4 |
Positive Sample: | LO2,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 34kDa |
Observed MW: | 38kDa |
This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55211 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |