The DPP8 Polyclonal Antibody (CAB7113) is a valuable tool for researchers studying DPP8, a serine peptidase involved in various physiological processes, including immune regulation and cell proliferation. This antibody, raised in rabbits, has been proven to be highly specific for human samples and is suitable for use in Western blot applications.DPP8, a member of the prolyl oligopeptidase family, plays a crucial role in regulating the immune response by cleaving and inactivating certain cytokines and chemokines. Dysregulation of DPP8 has been implicated in autoimmune diseases, cancer, and inflammatory conditions, making it an important target for therapeutic research.
By binding specifically to the DPP8 protein, this antibody enables researchers to detect and analyze its expression in various cell types, providing valuable insights into its function and potential role in disease pathology. Understanding the functions of DPP8 is essential for developing targeted therapies that can modulate immune responses and potentially treat a variety of disorders.
Product Name:
DPP8 Rabbit Polyclonal Antibody
SKU:
CAB7113
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-230 of human DPP8 (NP_932065.1).
This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
54878
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DPP8 antibody (CAB7113) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
