The DPP3 Polyclonal Antibody (CAB7054) is a valuable tool for researchers studying DPP3, a cell surface enzyme involved in various physiological processes. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the DPP3 protein, researchers can effectively detect and analyze its expression in different cell types, making it ideal for investigations in biochemistry and cancer research.DPP3, also known as dipeptidyl peptidase 3, plays a pivotal role in cellular metabolism and signaling pathways, making it a key target for research into diseases such as cancer, metabolic disorders, and cardiovascular diseases.
Understanding the function of DPP3 is essential for developing targeted therapies that can modulate its activity and influence cellular processes in disease states.Overall, the DPP3 Polyclonal Antibody (CAB7054) offers researchers a reliable tool for studying the role of DPP3 in various biological processes and disease mechanisms, ultimately paving the way for the development of novel therapeutic interventions.
Product Name:
DPP3 Rabbit Polyclonal Antibody
SKU:
CAB7054
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DPP3 (NP_569710.2).
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10072
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DPP3 antibody (CAB7054) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
