The Dopey1 monoclonal antibody (PACO18484) is a valuable tool for researchers studying the Dopey1 protein, an important regulator of cell proliferation and differentiation. This antibody, produced through a unique monoclonal antibody development process, demonstrates high specificity and sensitivity for detecting Dopey1 in a variety of experimental settings.Dopey1, also known as Dopey family member 1, is a key player in cellular processes such as cell cycle regulation and embryonic development. Dysregulation of Dopey1 has been linked to various diseases, including cancer and developmental disorders.
By utilizing the Dopey1 monoclonal antibody, researchers can explore the functions and mechanisms of Dopey1 in different cell types and experimental models.This antibody is validated for use in techniques such as Western blotting, immunofluorescence, and immunohistochemistry, providing researchers with versatile options for detecting and analyzing Dopey1 expression. Its high affinity and specificity make it a reliable tool for immunology, cell biology, and cancer research studies focused on understanding the role of Dopey1 in health and disease.
Antibody Name:
DOPEY1 Antibody (PACO18484)
Antibody SKU:
PACO18484
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human DOPEY2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18484(DOPEY1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18484(DOPEY1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene belongs to the dopey family. It is a transporter protein, possibly involved in protein traffic between late Golgi and early endosomes. This gene plays a potential role in functional brain alterations and in the pathogenesis of mental retardation in Down syndrome, it overexpression in the brain regions, that are altered in Down syndrome patients and involved in learning and memory processes.
Synonyms:
dopey family member 1
UniProt Protein Function:
DOPEY1: May be involved in protein traffic between late Golgi and early endosomes. Belongs to the dopey family.Protein type: VesicleChromosomal Location of Human Ortholog: 6q15Biological Process: protein transport