The DOPEY1 Polyclonal Antibody (PACO18483) is a valuable tool for research involving the DOPEY1 protein, a critical player in cellular processes and signaling pathways. This high-quality antibody, generated in rabbits, exhibits excellent reactivity with human samples and is validated for use in various applications, including Western blot analysis. By specifically binding to the DOPEY1 protein, this antibody facilitates the detection and analysis of DOPEY1 in different cell types, making it a versatile option for studies in molecular biology and genetics.
DOPEY1, also known as a key regulator of cell division, is involved in the coordination of mitotic events and is essential for proper cell cycle progression. Its importance in cellular functions makes it a promising target for research in areas such as cancer biology, developmental biology, and genetic disorders. Understanding the role of DOPEY1 in these contexts is crucial for unraveling its functional mechanisms and potential therapeutic implications.
Antibody Name:
DOPEY1 Antibody (PACO18483)
Antibody SKU:
PACO18483
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human DOPEY1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18483(DOPEY1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18483(DOPEY1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene belongs to the dopey family. It is a transporter protein, possibly involved in protein traffic between late Golgi and early endosomes. This gene plays a potential role in functional brain alterations and in the pathogenesis of mental retardation in Down syndrome, it overexpression in the brain regions, that are altered in Down syndrome patients and involved in learning and memory processes.
Synonyms:
dopey family member 1
UniProt Protein Function:
DOPEY1: May be involved in protein traffic between late Golgi and early endosomes. Belongs to the dopey family.Protein type: VesicleChromosomal Location of Human Ortholog: 6q15Biological Process: protein transport