Dopamine Receptor D3 (DRD3) Rabbit Monoclonal Antibody (CAB4587)
- SKU:
- CAB4587
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Dopamine Receptor D3 (DRD3) Rabbit Monoclonal Antibody |
SKU: | CAB4587 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Dopamine Receptor D3 (DRD3) (P35462). |
Sequence: | MASL SQLS GHLN YTCG AENS TGAS QARP HAYY ALSY CALI LAIV FGNG LVCM AVLK ERAL QTTT NYLV VSLA VADL LVAT LVMP WVVY LEVT GGVW NFSR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | D3DR; ETM1; FET1; Dopamine Receptor D3 (DRD3) |
Positive Sample: | HeLa,C6,SH-SY5Y,U-251MG,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 44kDa |
Observed MW: | 50kDa |
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Purification Method: | Affinity purification |
Gene ID: | 1814 |
Clone Number: | ARC1041 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |