The Dopamine Receptor D3 Rabbit Monoclonal Antibody (CAB4587) is a cutting-edge tool for researchers studying dopamine receptor D3, a G protein-coupled receptor involved in the regulation of various physiological functions such as locomotion, emotion, and reward. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples and is validated for use in Western blot and immunohistochemistry applications.By targeting the dopamine receptor D3 protein, this antibody allows for precise detection and localization of this important receptor in different cell types and tissues. This makes it an invaluable resource for neuroscientists and pharmacologists conducting research on dopamine signaling pathways and their implications in neurological disorders, addiction, and mental health conditions.
The dopamine receptor D3 antibody opens up new avenues for understanding the role of this receptor in normal brain function and its potential involvement in various neurological diseases. Its reliability and accuracy make it a crucial tool for investigating the complex mechanisms underlying dopaminergic signaling, paving the way for innovative therapeutic strategies targeting dopamine receptors.
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Purification Method:
Affinity purification
Gene ID:
1814
Clone Number:
ARC1041
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Dopamine Receptor D3 (DRD3) Rabbit mAb (CAB4587) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
