DOK6 Antibody (PACO08917)
- SKU:
- PACO08917
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
DOK6 Antibody (PACO08917)
The DOK6 Antibody (PACO08917) is a polyclonal antibody designed for research involving DOK6, a cytoplasmic protein that plays a critical role in cell signaling pathways and immune regulation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to DOK6, this antibody enables researchers to detect and analyze the protein in various cell types, facilitating studies in immunology, cell biology, and cancer research.
DOK6 is known for its involvement in important cellular processes such as cell growth, differentiation, and survival. Its role in immune regulation makes it a promising target for research into diseases like cancer, autoimmune disorders, and inflammatory conditions. By studying the function of DOK6, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic strategies for treating them.
| Antibody Name: | DOK6 Antibody (PACO08917) |
| Antibody SKU: | PACO08917 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human DOK6 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | docking protein 6;DOK6;DOK5L;HsT3226;MGC20785 ; |
| UniProt Protein Function: | DOK6: ocking proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. Interacts via its PTB domain with phosphorylated Ret, promoting neurite growth. May have a role in brain development and/or maintenance. Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 18q22.2 Molecular Function:insulin receptor binding; protein binding |
| NCBI Summary: | DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q6PKX4 |
| NCBI GenInfo Identifier: | 84029601 |
| NCBI Gene ID: | 220164 |
| NCBI Accession: | Q6PKX4.1 |
| UniProt Secondary Accession: | Q6PKX4,Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2, A6NNG3, |
| UniProt Related Accession: | Q6PKX4 |
| Molecular Weight: | 38,318 Da |
| NCBI Full Name: | Docking protein 6 |
| NCBI Synonym Full Names: | docking protein 6 |
| NCBI Official Symbol: | DOK6Â Â |
| NCBI Official Synonym Symbols: | DOK5L; HsT3226Â Â |
| NCBI Protein Information: | docking protein 6 |
| UniProt Protein Name: | Docking protein 6 |
| UniProt Synonym Protein Names: | Downstream of tyrosine kinase 6 |
| Protein Family: | Docking protein |
| UniProt Gene Name: | DOK6Â Â |
| UniProt Entry Name: | DOK6_HUMAN |
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