The DODA Polyclonal Antibody (PACO58220) is a valuable tool for researchers studying DODA, a key enzyme involved in the biosynthesis of the pigment melanin. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting DODA in various samples, particularly in Western blot applications.DODA, also known as L-DOPA dioxygenase, plays a crucial role in the conversion of L-DOPA to dopachrome, a critical step in melanin production.
Dysregulation of DODA has been linked to pigmentation disorders and melanoma, making it a promising target for further investigation. By using the DODA Polyclonal Antibody, researchers can gain insights into the expression and activity of DODA in different cellular contexts, aiding in the development of potential therapies for skin conditions and melanoma.
Antibody Name:
DODA Antibody (PACO58220)
Antibody SKU:
PACO58220
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Portulaca grandiflora
Immunogen:
Recombinant Portulaca grandiflora 4,5-DOPA dioxygenase extradiol protein (1-271AA)
Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid,
Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid.
