The Docking Protein 4 Polyclonal Antibody (CAB0226) is a versatile tool designed for research involving Docking Protein 4 (Dok-4), a protein involved in cell signaling pathways and regulation of cellular processes. The antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to Dok-4, this antibody enables accurate detection and analysis of the protein in a variety of cell types, making it an essential asset for studies in molecular biology, cell signaling, and cancer research.Dok-4 plays a crucial role in mediating signal transduction events within cells, particularly in response to growth factors and cytokines.
Its involvement in regulating cell proliferation, differentiation, and survival underscores its importance in various physiological and pathological processes. Research focused on Dok-4 provides valuable insights into cellular mechanisms underlying cancer development, neurodegenerative diseases, and metabolic disorders. By elucidating the functions of Dok-4, scientists can advance the development of targeted therapies for conditions influenced by dysregulated cell signaling pathways.
Product Name:
DOK4 Rabbit Polyclonal Antibody
SKU:
CAB0226
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human DOK4 (NP_060580.2).
Predicted to be involved in positive regulation of MAPK cascade and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within nervous system development. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
55715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DOK4 Rabbit pAb (CAB0226) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
