UniProt Protein Function: | DOCK9: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation. Belongs to the DOCK family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; GAPs, Rac/RhoChromosomal Location of Human Ortholog: 13q32.3Cellular Component: membrane; endomembrane system; cytosolMolecular Function: Rho guanyl-nucleotide exchange factor activity; protein binding; Rho GTPase bindingBiological Process: small GTPase mediated signal transduction; blood coagulation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9BZ29 |
NCBI GenInfo Identifier: | 194239705 |
NCBI Gene ID: | 23348 |
NCBI Accession: | NP_001123520.1 |
UniProt Secondary Accession: | Q9BZ29,Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26 Q9BZ27, Q9BZ28, Q9UPU4 |
UniProt Related Accession: | Q9BZ29 |
Molecular Weight: | Calculated MW: 239kDaObserved MW: 200-236kDa |
NCBI Full Name: | dedicator of cytokinesis protein 9 isoform b |
NCBI Synonym Full Names: | dedicator of cytokinesis 9 |
NCBI Official Symbol: | DOCK9Â Â |
NCBI Official Synonym Symbols: | ZIZ1; ZIZIMIN1Â Â |
NCBI Protein Information: | dedicator of cytokinesis protein 9; cdc42 guanine nucleotide exchange factor zizimin-1 |
UniProt Protein Name: | Dedicator of cytokinesis protein 9 |
UniProt Synonym Protein Names: | Cdc42 guanine nucleotide exchange factor zizimin-1 |
Protein Family: | Dedicator of cytokinesis protein |
UniProt Gene Name: | DOCK9Â Â |
UniProt Entry Name: | DOCK9_HUMAN |