The DOCK9 Polyclonal Antibody (PACO08911) is a valuable tool for researchers studying the DOCK9 protein, which plays a key role in cell migration and cytoskeletal reorganization. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting DOCK9 in human samples, making it suitable for use in Western blotting and immunohistochemistry applications.DOCK9 is a guanine nucleotide exchange factor that activates the Rho GTPase Cdc42, thereby influencing cell morphology and motility. Its involvement in regulating actin dynamics makes it a focal point for investigations in cell biology, cancer metastasis, and neuronal development.
By targeting DOCK9, researchers can elucidate its function in various cellular processes and potentially uncover new therapeutic targets for diseases related to cell motility and invasion.With its reliable performance and versatility in detecting DOCK9 expression, the PACO08911 antibody is an essential tool for unlocking the mysteries of DOCK9 biology and its implications in health and disease.
dedicator of cytokinesis 9;DOCK9;DKFZp686C11110;DKFZp686D2047;DKFZp686N04132;FLJ11949;FLJ16744;FLJ44528;FLJ45282;FLJ45601;KIAA1058;KIAA1085;ZIZ1;ZIZIMIN1 ;
UniProt Protein Function:
DOCK9: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation. Belongs to the DOCK family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; GAPs, Rac/RhoChromosomal Location of Human Ortholog: 13q32.3Cellular Component: membrane; endomembrane system; cytosolMolecular Function: Rho guanyl-nucleotide exchange factor activity; protein binding; Rho GTPase bindingBiological Process: small GTPase mediated signal transduction; blood coagulation
