DOCK7 Rabbit Polyclonal Antibody (CAB17236)
- SKU:
- CAB17236
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | DOCK7 Rabbit Polyclonal Antibody |
SKU: | CAB17236 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DOCK7 (NP_001354490.1). |
Sequence: | VSAV PEES EMDP HVRD CIRS YTED WAIV IRKY HKLG TGFN PNTL DKQK ERQK GLPK QVFE SDEA PDGN SYQD DQDD LKRR SMSI DDTP RGSW ACSI FDLK N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ZIR2; DEE23; EIEE23; DOCK7 |
Positive Sample: | HeLa,Jurkat,U-87MG,Mouse brain,Mouse ovary,Rat brain |
Cellular Localization: | axon, growth cone, neuron projection |
Calculated MW: | 243kDa |
Observed MW: | 250kDa |
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 85440 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |