The Dock1 Polyclonal Antibody (CAB17359) is a valuable tool for researchers studying Dock1, a protein involved in cell signaling and cytoskeleton regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and is specifically designed for use in Western blot applications. By binding to the Dock1 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for research in cell biology and cancer biology.Dock1, also known as dedicator of cytokinesis 1, plays a crucial role in cell migration, adhesion, and invasion, making it a key player in cancer progression and metastasis.
Understanding the function of Dock1 is vital for unraveling the mechanisms behind these processes and identifying potential therapeutic targets for cancer treatment. The Dock1 Polyclonal Antibody (CAB17359) provides researchers with a reliable tool to explore the role of Dock1 in cellular processes, paving the way for advancements in cancer research and drug development.
Product Name:
DOCK1 Rabbit Polyclonal Antibody
SKU:
CAB17359
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1766-1865 of human DOCK1 (NP_001371.1).
This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1793
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using DOCK1 Rabbit pAb (CAB17359) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
