DNTT Rabbit Polyclonal Antibody (CAB6254)
- SKU:
- CAB6254
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | DNTT Rabbit Polyclonal Antibody |
SKU: | CAB6254 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-509 of human TdT (NP_004079.3). |
Sequence: | LKTS EKWF RMGF RTLS KVRS DKSL KFTR MQKA GFLY YEDL VSCV TRAE AEAV SVLV KEAV WAFL PDAF VTMT GGFR RGKK MGHD VDFL ITSP GSTE DEEQ LLQK VMNL WEKK GLLL YYDL VEST FEKL RLPS RKVD ALDH FQKC FLIF KLPR QRVD SDQS SWQE GKTW KAIR VDLV LCPY ERRA FALL GWTG SRQF ERDL RRYA THER KMIL DNHA LYDK TKRI FLKA ESEE EIFA HLGL DYIE PWER NA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | TDT; TdT |
Positive Sample: | Jurkat,Molt-4,HL-60,Mouse liver,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 59kDa |
Observed MW: | 55kDa/58kDa |
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Purification Method: | Affinity purification |
Gene ID: | 1791 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |