The DNPH1 Polyclonal Antibody (CAB17617) is a valuable tool for research involving DNPH1, a key enzyme involved in DNA damage repair and oxidative stress response. This rabbit polyclonal antibody is highly specific to human samples and is suitable for use in Western blot applications. It binds specifically to DNPH1, allowing for accurate detection and analysis in a variety of cell types.DNPH1 is essential for repairing DNA damage caused by reactive oxygen species and other environmental factors.
Its role in maintaining genomic stability and protecting cells from oxidative stress makes it a vital target for research in fields such as cancer biology, aging, and neurodegenerative diseases. Understanding the function of DNPH1 can provide insights into mechanisms of DNA repair and potential therapeutic strategies for conditions associated with DNA damage and oxidative stress.
Product Name:
DNPH1 Rabbit Polyclonal Antibody
SKU:
CAB17617
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human DNPH1 (NP_006434.1).
This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described.
Purification Method:
Affinity purification
Gene ID:
10591
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNPH1 Rabbit pAb (CAB17617) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.