DNMT3A Rabbit Polyclonal Antibody (CAB2065)
- SKU:
- CAB2065
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DNMT3A Rabbit Polyclonal Antibody |
SKU: | CAB2065 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-132 of human DNMT3A (NP_072046.2). |
Sequence: | MPAM PSSG PGDT SSSA AERE EDRK DGEE QEEP RGKE ERQE PSTT ARKV GRPG RKRK HPPV ESGD TPKD PAVI SKSP SMAQ DSGA SELL PNGD LEKR SEPQ PEEG SPAG GQKG GAPA EGEG AAET LPEA SRAV |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | TBRS; HESJAS; DNMT3A2; M.HsaIIIA; DNMT3A |
Positive Sample: | A-549,293T,HeLa,HL-60,MCF7,HepG2,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 102kDa |
Observed MW: | 110kDa/130kDa |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Purification Method: | Affinity purification |
Gene ID: | 1788 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |