DNM1L Polyclonal Antibody (CAB21311)
- SKU:
- CAB21311
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Frequently bought together:
Description
Product Name: | DNM1L Polyclonal Antibody |
SKU: | CAB21311 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 437-736 of human DNM1L (NP_036192.2). |
Sequence: | EEMQ RIIQ HCSN YSTQ ELLR FPKL HDAI VEVV TCLL RKRL PVTN EMVH NLVA IELA YINT KHPD FADA CGLM NNNI EEQR RNRL AREL PSAV SRDK SSKV PSAL APAS QEPS PAAS AEAD GKLI QDSR RETK NVAS GGGG VGDG VQEP TTGN WRGM LKTS KAEE LLAE EKSK PIPI MPAS PQKG HAVN LLDV PVPV ARKL SARE QRDC EVIE RLIK SYFL IVRK NIQD SVPK AVMH FLVN HVKD TLQS ELVG QLYK SSLL DDLL TESE DMAQ RRKE AADM LKAL QGAS QIIA EIRE THLW |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV; DNM1L |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Golgi apparatus, Membrane, Mitochondrion outer membrane, Peripheral membrane protein, Peroxisome, clathrin-coated pit, cytosol, secretory vesicle, synaptic vesicle membrane. |
Calculated MW: | 82kDa |
Observed MW: | Refer to figures |
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 10059 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |