DRP1 Rabbit Polyclonal Antibody (CAB2586)
- SKU:
- CAB2586
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DRP1 Rabbit Polyclonal Antibody |
SKU: | CAB2586 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 411-710 of human DRP1 (NP_036193.2). |
Sequence: | VSFE LLVK RQIK RLEE PSLR CVEL VHEE MQRI IQHC SNYS TQEL LRFP KLHD AIVE VVTC LLRK RLPV TNEM VHNL VAIE LAYI NTKH PDFA DACG LMNN NIEE QRRN RLAR ELPS AVSR DKLI QDSR RETK NVAS GGGG VGDG VQEP TTGN WRGM LKTS KAEE LLAE EKSK PIPI MPAS PQKG HAVN LLDV PVPV ARKL SARE QRDC EVIE RLIK SYFL IVRK NIQD SVPK AVMH FLVN HVKD TLQS ELVG QLYK SSLL DDLL TESE DMAQ RRKE AADM LKAL QGAS QIIA EIRE THLW |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Golgi apparatus, Membrane, Mitochondrion outer membrane, Peripheral membrane protein, Peroxisome, clathrin-coated pit, cytosol, secretory vesicle, synaptic vesicle membrane. |
Calculated MW: | 82kDa |
Observed MW: | 78kDa |
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 10059 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |