The DNER Polyclonal Antibody (CAB15551) is a highly specific research tool designed for studying DNER, a cell surface protein involved in neural development and signal transduction. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is suitable for Western blot applications. By binding to the DNER protein, it allows for the accurate detection and analysis of DNER expression in a variety of cell types, making it ideal for neuroscience and developmental biology research.DNER, also known as Delta/Notch-like EGF-related receptor, plays a crucial role in mediating cell-to-cell communication and regulating neuronal activity.
Its involvement in neuronal differentiation and synaptic plasticity makes it a promising target for investigation in neurological disorders and brain development studies. By elucidating the functions of DNER, researchers can gain valuable insights into the mechanisms underlying neurodevelopmental disorders and potentially uncover novel therapeutic strategies for treating these conditions.
Product Name:
DNER Rabbit Polyclonal Antibody
SKU:
CAB15551
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DNER (NP_620711.3).
Hela,HT-29,Mouse brain,Mouse eye,Mouse small intestine,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
78kDa
Observed MW:
80kDa
Predicted to enable Notch binding activity. Involved in central nervous system development. Located in dendrite; early endosome; and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
92737
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNER Rabbit pAb (CAB15551) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
