The DNAse1L1 Polyclonal Antibody (CAB13150) is a valuable tool for researchers studying DNAse1L1, an enzyme involved in the degradation of DNA and RNA in cells. This antibody, produced using rabbits as hosts, is highly specific for human samples and has been validated for use in Western blot applications. By binding to DNAse1L1, this antibody enables the detection and analysis of this enzyme in a variety of cell types, making it an ideal choice for studies in molecular biology and cell signaling pathways.
DNAse1L1 plays a critical role in maintaining cellular health by breaking down nucleic acids released by dying cells, thereby preventing inflammation and tissue damage. Dysregulation of DNAse1L1 activity has been linked to various diseases, including autoimmune disorders, neurodegenerative diseases, and cancer. By studying the function of DNAse1L1 using this antibody, researchers can gain valuable insights into disease mechanisms and potentially develop novel therapeutic strategies targeting this enzyme.
Product Name:
DNASE1L1 Rabbit Polyclonal Antibody
SKU:
CAB13150
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human DNASE1L1 (NP_006721.1).
This gene encodes a deoxyribonuclease protein that shows high sequence similarity to DNase I. The encoded protein is localized to the endoplasmic reticulum and modified by N-linked glycosylation. Alternate transcriptional splice variants encoding the same protein have been observed.
Purification Method:
Affinity purification
Gene ID:
1774
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using DNASE1L1 Rabbit pAb (CAB13150) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
