The DNAJC7 Polyclonal Antibody (CAB2780) is a valuable tool for researchers studying DNAJC7, a protein involved in regulating protein folding and quality control in the cell. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications, enabling reliable detection and analysis of DNAJC7 in a variety of cell types.DNAJC7 is a member of the Heat shock protein 40 (Hsp40) family, which plays a critical role in assisting in the folding of newly synthesized proteins and in the disaggregation of misfolded proteins. Dysregulation of DNAJC7 has been implicated in various diseases, including neurodegenerative disorders and cancer.
By studying the function of DNAJC7, researchers can gain insight into the molecular mechanisms underlying these diseases and potentially identify therapeutic targets for intervention.With its high specificity and reliability in Western blotting, the DNAJC7 Polyclonal Antibody (CAB2780) is an essential tool for scientists conducting research in the fields of molecular biology, cell biology, and disease pathology. By using this antibody, researchers can further our understanding of the role of DNAJC7 in health and disease, ultimately paving the way for the development of novel treatment strategies for a range of conditions.
Product Name:
DNAJC7 Rabbit Polyclonal Antibody
SKU:
CAB2780
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human DNAJC7 (NP_003306.3).
This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7266
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DNAJC7 antibody (CAB2780) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
