The DNAJC5 Polyclonal Antibody (CAB10489) is a valuable tool for researchers studying DNAJC5, a protein involved in synaptic vesicle trafficking and neurotransmitter release. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By targeting the DNAJC5 protein, researchers can investigate its role in neuronal function and potentially uncover new insights into neurological disorders such as Parkinson's disease and epilepsy.DNAJC5, also known as cysteine-string protein alpha, is essential for maintaining proper synaptic transmission and neuronal viability.
Dysregulation of DNAJC5 has been implicated in various neurodegenerative diseases, making it a key target for therapeutic interventions aimed at preserving neuronal health and function. By using the DNAJC5 Polyclonal Antibody, researchers can delve deeper into the mechanisms underlying these disorders and potentially uncover novel treatment strategies for improving patient outcomes.
Product Name:
DNAJC5 Rabbit Polyclonal Antibody
SKU:
CAB10489
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DNAJC5 (NP_079495.1).
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.
Purification Method:
Affinity purification
Gene ID:
80331
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNAJC5 Rabbit pAb (CAB10489) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
