The DNAJC30 Polyclonal Antibody (PACO39334) is a valuable tool for research involving DNAJC30, a member of the DnaJ/Hsp40 family of proteins known to be involved in protein folding and unfolding processes within the cell. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the DNAJC30 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cell biology research.DNAJC30 is known to play a crucial role in maintaining protein homeostasis and ensuring proper cellular function. Its involvement in protein quality control processes makes it a key player in preventing the accumulation of misfolded proteins that can lead to various diseases, including neurodegenerative disorders and cancer.
Research into the functions and mechanisms of DNAJC30 is essential for gaining a better understanding of cellular processes and developing targeted therapies for diseases related to protein misfolding and aggregation.Overall, the DNAJC30 Polyclonal Antibody (PACO39334) offers researchers a reliable and specific tool for studying the roles and functions of DNAJC30 in cellular physiology and disease mechanisms, ultimately contributing to advances in the fields of molecular biology and biomedicine.
Immunohistochemistry of paraffin-embedded human brain tissue using PACO39334 at dilution of 1:100.
Western blot. All lanes: DNAJC30 antibody at 10µg/ml. Lane 1: 293T whole cell lysate. Lane 2: U87 whole cell lysate. Lane 3: SH-SY5Y whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 26 kDa. Observed band size: 26, 90 kDa.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39334 at dilution of 1:100.
Synonyms:
DnaJ homolog subfamily C member 30 (Williams-Beuren syndrome chromosomal region 18 protein), DNAJC30, WBSCR18
UniProt Protein Function:
DNAJC30: DNAJC30 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.Protein type: Mitochondrial; ChaperoneChromosomal Location of Human Ortholog: 7q11.23
UniProt Protein Details:
NCBI Summary:
This intronless gene encodes a member of the DNAJ molecular chaperone homology domain-containing protein family. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Jul 2008]
