DNAJC2 Rabbit Polyclonal Antibody (CAB4633)
- SKU:
- CAB4633
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DNAJC2
- MPHOSPH11
- MPP11
- ZRF1
- ZUO1
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | DNAJC2 Rabbit Polyclonal Antibody |
SKU: | CAB4633 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DNAJC2 (NP_055192.1). |
Sequence: | MLLL PSAA DGRG TAIT HALT SAST LCQV EPVG RWFE AFVK RRNR NASA SFQE LEDK KELS EESE DEEL QLEE FPML KTLD PKDW KNQD HYAV LGLG HVRY KATQ RQIK AAHK AMVL KHHP DKRK AAGE PIKE GDND YFTC |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ZRF1; ZUO1; MPP11; MPHOSPH11; DNAJC2 |
Positive Sample: | HeLa,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, cytosol. |
Calculated MW: | 72kDa |
Observed MW: | 80kDa |
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 27000 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |