The DNAJC18 Polyclonal Antibody (CAB17843) is a valuable tool for research involving DNAJC18, a protein involved in protein folding and chaperone activity. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the DNAJC18 protein, allowing for its detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and protein folding mechanisms.DNAJC18 is known to interact with heat shock proteins and aid in protein folding, as well as play a role in cellular stress responses.
Understanding the function of DNAJC18 is crucial for unraveling its involvement in diseases related to protein misfolding, such as neurodegenerative disorders and certain types of cancer. This antibody can help researchers uncover the mechanisms by which DNAJC18 contributes to these diseases, potentially leading to novel therapeutic targets and treatment strategies.
Product Name:
DNAJC18 Rabbit Polyclonal Antibody
SKU:
CAB17843
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 260-350 of human DNAJC18 (NP_689899.1).
Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein; chaperone cofactor-dependent protein refolding; and ubiquitin-dependent ERAD pathway. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane.
Purification Method:
Affinity purification
Gene ID:
202052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNAJC18 Rabbit pAb (CAB17843) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 300s.
