The DNAJB11 Polyclonal Antibody (CAB12915) is a valuable tool for researchers studying DNAJB11, a key protein involved in protein folding and chaperone activity within cells. This antibody, produced in rabbits, shows high specificity towards human samples and has been rigorously validated for use in Western blot applications.DNAJB11, also known as DnaJ homolog subfamily B member 11, plays a crucial role in assisting in the correct folding of proteins, particularly during times of cellular stress. Dysfunction of DNAJB11 has been implicated in various diseases, including neurodegenerative disorders and cancer.
Understanding the function and regulation of DNAJB11 is critical for developing targeted therapies for these conditions.With its high reactivity and specificity, the DNAJB11 Polyclonal Antibody enables researchers to detect and analyze DNAJB11 expression in a variety of cell types and experimental conditions. This makes it an essential tool for investigations into protein folding mechanisms, chaperone activity, and their implications in disease pathology.
Product Name:
DNAJB11 Rabbit Polyclonal Antibody
SKU:
CAB12915
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 89-358 of human DNAJB11 (NP_057390.1).
This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity.
Purification Method:
Affinity purification
Gene ID:
51726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNAJB11 Rabbit pAb (CAB12915) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
