The DNAJA2 Polyclonal Antibody (CAB7059) is a valuable tool for researchers studying DNAJA2, a member of the heat shock protein family involved in protein folding and cellular stress response. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the DNAJA2 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in molecular biology and cell stress research.DNAJA2, also known as heat shock protein HSP40, plays a crucial role in assisting protein folding and preventing misfolding under stressful conditions.
Its involvement in cellular stress response makes it a key focus for research into diseases such as neurodegenerative disorders, cancer, and cardiovascular diseases. By understanding the function of DNAJA2, researchers can gain insights into the mechanisms of cellular stress and potentially identify new therapeutic targets for managing stress-related diseases.Overall, the DNAJA2 Polyclonal Antibody (CAB7059) provides a reliable tool for studying the functions and implications of DNAJA2 in cellular stress response, offering valuable insights for further advancements in biomedical research and drug discovery.
Product Name:
DNAJA2 Rabbit Polyclonal Antibody
SKU:
CAB7059
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 233-412 of human DNAJA2 (NP_005871.1).
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
Purification Method:
Affinity purification
Gene ID:
10294
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DNAJA2 antibody (CAB7059) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
