DNAJA1 Rabbit Polyclonal Antibody (CAB11602)
- SKU:
- CAB11602
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DNAJA1 Rabbit Polyclonal Antibody |
SKU: | CAB11602 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 178-397 of human DNAJA1 (NP_001530.1). |
Sequence: | MECQ GHGE RISP KDRC KSCN GRKI VREK KILE VHID KGMK DGQK ITFH GEGD QEPG LEPG DIII VLDQ KDHA VFTR RGED LFMC MDIQ LVEA LCGF QKPI STLD NRTI VITS HPGQ IVKH GDIK CVLN EGMP IYRR PYEK GRLI IEFK VNFP ENGF LSPD KLSL LEKL LPER KEVE ETDE MDQV ELVD FDPN QERR RHYN GEAY EDDE HHPR GGVQ CQTS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 |
Synonyms: | DJ-2; DjA1; HDJ2; HSDJ; HSJ2; HSJ-2; HSPF4; NEDD7; hDJ-2; A1 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Lipid-anchor, Membrane, Microsome, Mitochondrion, Nucleus, perinuclear region. |
Calculated MW: | 45kDa |
Observed MW: | 45kDa |
This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes.
Purification Method: | Affinity purification |
Gene ID: | 3301 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |