DNA Polymerase beta Rabbit Monoclonal Antibody (CAB2412)
The DNA Polymerase Beta Rabbit Monoclonal Antibody (CAB2412) is a highly specific antibody designed for research involving DNA polymerase beta, a key enzyme involved in DNA repair and replication processes. This antibody, produced in rabbits, is exceptionally reactive with human samples and has been validated for use in Western blot applications. DNA polymerase beta is crucial for maintaining genomic stability and fidelity, making it a critical player in cellular processes such as DNA damage repair and replication. This antibody binds specifically to the DNA polymerase beta protein, enabling accurate detection and analysis in a variety of cell types.
With its ability to detect DNA polymerase beta, this antibody is ideal for use in studies related to DNA repair mechanisms, mutagenesis, and cancer research. By understanding the role of DNA polymerase beta in these processes, researchers can gain valuable insights into the mechanisms underlying diseases such as cancer and genetic disorders. Overall, the DNA Polymerase Beta Rabbit Monoclonal Antibody (CAB2412) is a valuable tool for scientists looking to investigate the function of DNA polymerase beta and its implications in various cellular processes and diseases.
Product Name:
DNA Polymerase beta Rabbit Monoclonal Antibody
SKU:
CAB2412
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 236-335 of human DNA Polymerase beta (P06746).
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.
Purification Method:
Affinity purification
Gene ID:
5423
Clone Number:
ARC0752
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNA Polymerase beta Rabbit mAb (CAB2412) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
