The DLX5 Polyclonal Antibody (CAB15049) is a key tool for researchers studying the DLX5 protein, which plays a crucial role in development and differentiation of various tissues and organs, including bones and teeth. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards DLX5 in human samples, enabling accurate detection and analysis in Western blot applications.DLX5, a member of the homeobox transcription factor family, is known to regulate gene expression in a variety of biological processes, such as embryonic development and cell fate determination.
Its dysregulation has been linked to various diseases, making it a promising target for research in developmental biology, skeletal disorders, and cancer.By utilizing the DLX5 Polyclonal Antibody, researchers can explore the molecular mechanisms underlying DLX5 function, paving the way for potential therapeutic interventions targeting DLX5-related pathways. This antibody is a valuable tool for investigating the role of DLX5 in normal physiology and disease pathology, offering insights into potential diagnostic and treatment strategies.
Product Name:
DLX5 Rabbit Polyclonal Antibody
SKU:
CAB15049
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human DLX5 (NP_005212.1).
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
Purification Method:
Affinity purification
Gene ID:
1749
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DLX5 antibody (CAB15049) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.