DLX4 Antibody (PACO00710)
- SKU:
- PACO00710
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
DLX4 Antibody (PACO00710)
The DLX4 Polyclonal Antibody (PACO00710) is specifically designed for research involving DLX4, a transcription factor involved in embryonic development and cell differentiation. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.DLX4 plays a crucial role in the regulation of gene expression during development, particularly in the formation of various tissues and organs. Its dysregulation has been implicated in various diseases including cancer, genetic disorders, and developmental abnormalities.
The DLX4 antibody enables researchers to detect and analyze the expression of DLX4 in different cell types, making it a valuable tool for studies in developmental biology and cancer research.Understanding the function of DLX4 is essential for uncovering its role in disease pathogenesis and potentially developing targeted therapies. By utilizing the DLX4 Polyclonal Antibody, researchers can further investigate the molecular mechanisms underlying DLX4 function and its contribution to various pathological processes.
| Antibody Name: | DLX4 Antibody |
| Antibody SKU: | PACO00710 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human Dlx-4. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | DLX4; BP1; DLX7; DLX8; DLX9; Homeobox protein DLX-4; Beta protein 1; Homeobox protein DLX-7; Homeobox protein DLX-8 |
| UniProt Protein Function: | DLX4: May play a role in determining the production of hemoglobin S. May act as a repressor. Belongs to the distal-less homeobox family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 17q21.33 Molecular Function:protein binding; sequence-specific DNA binding Biological Process: negative regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92988 |
| NCBI GenInfo Identifier: | 85700416 |
| NCBI Gene ID: | 1748 |
| NCBI Accession: | Q92988.4 |
| UniProt Secondary Accession: | Q92988,O60480, Q13265, Q6PJK0, Q9HBE0, D3DTX2, D3DTX3 |
| UniProt Related Accession: | Q92988 |
| Molecular Weight: | 12,713 Da |
| NCBI Full Name: | Homeobox protein DLX-4 |
| NCBI Synonym Full Names: | distal-less homeobox 4 |
| NCBI Official Symbol: | DLX4Â Â |
| NCBI Official Synonym Symbols: | BP1; DLX7; DLX8; DLX9; OFC15Â Â |
| NCBI Protein Information: | homeobox protein DLX-4 |
| UniProt Protein Name: | Homeobox protein DLX-4 |
| UniProt Synonym Protein Names: | Beta protein 1; Homeobox protein DLX-7; Homeobox protein DLX-8 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | DLX4Â Â |
| UniProt Entry Name: | DLX4_HUMAN |
Related Products
DLX4 Antibody (PACO08860)
DLX4 Antibody (PACO21918)
DLX4 Antibody (PACO16191)
DLX4 Antibody (PACO16190)
DLX4 Colorimetric Cell-Based ELISA
