The DLX2 Polyclonal Antibody (CAB8410) is a valuable tool for research involving DLX2, a transcription factor involved in the development of various tissues, including craniofacial structures and limbs. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the DLX2 protein, this antibody enables researchers to detect and analyze DLX2 expression in different cell types, making it ideal for studies in developmental biology and regenerative medicine.
DLX2 is a key player in the regulation of gene expression during embryonic development, particularly in the formation of the nervous system and skeletal structures. Its functions in cell differentiation and tissue patterning make it a crucial target for research into congenital disorders, birth defects, and tissue regeneration. Understanding the role of DLX2 is essential for advancing our knowledge of developmental processes and potential therapeutic interventions in related conditions.
Product Name:
DLX2 Rabbit Polyclonal Antibody
SKU:
CAB8410
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DLX2 (NP_004396.1).
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
Purification Method:
Affinity purification
Gene ID:
1746
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DLX2 antibody (CAB8410) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
