The DLL4 Polyclonal Antibody is a vital tool for researchers studying DLL4, a critical protein involved in the Notch signaling pathway and angiogenesis. Produced in rabbits, this antibody is highly specific to human DLL4 and has been validated for use in Western blot applications. By binding to DLL4, this antibody allows for the detection and analysis of DLL4 expression in various cell types, making it an essential asset for studies in cancer biology, developmental biology, and vascular biology.
DLL4, a transmembrane protein, plays a key role in regulating cell fate decisions and angiogenesis during development and in pathological conditions such as cancer. Understanding the function of DLL4 is crucial for elucidating its role in disease progression and for developing targeted therapies that modulate its activity. The DLL4 Polyclonal Antibody is a valuable tool for researchers aiming to uncover the mechanisms underlying DLL4 signaling and its implications in disease.
Product Name:
DLL4 Polyclonal Antibody
SKU:
CAB24862
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-524 of human DLL4 (NP_061947.1).
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
Purification Method:
Affinity purification
Gene ID:
54567
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with DLL4 using DLL4 Rabbit pAb(CAB24862) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
