The DLL3 Polyclonal Antibody (CAB18108) is a crucial tool for researchers studying DLL3, a protein involved in cell signaling pathways and development. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the DLL3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for investigations in developmental biology and cancer research.
DLL3, also known as Delta-like protein 3, plays a pivotal role in regulating cell differentiation and proliferation, making it a key player in various biological processes. Its involvement in cellular signaling pathways makes it a potential target for studying diseases such as cancer and developmental disorders. Understanding the function of DLL3 is vital for uncovering its role in normal development and disease progression, which could lead to the development of novel therapeutic strategies.
Product Name:
DLL3 Polyclonal Antibody
SKU:
CAB18108
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 520-618 of human DLL3 (NP_058637.1).
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
10683
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DLL3 antibody (CAB18108) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
