The DLL1 Polyclonal Antibody (CAB14277) is a valuable tool for researchers studying the Delta-like 1 (DLL1) protein, a key player in Notch signaling pathways. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting DLL1 in human samples, making it suitable for various research applications, including Western blot analysis.DLL1 is a transmembrane ligand that interacts with Notch receptors to regulate cell fate decisions, such as proliferation, differentiation, and apoptosis. Dysregulation of DLL1-Notch signaling has been implicated in various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities.
Therefore, understanding the role of DLL1 and its interactions is essential for advancing therapeutic strategies targeting the Notch pathway.By utilizing the DLL1 Polyclonal Antibody, researchers can investigate the expression levels, localization, and function of DLL1 in different cell types and experimental conditions. This antibody enables precise detection and analysis of DLL1 protein, providing valuable insights into its biological functions and potential as a therapeutic target. Explore the versatility of the DLL1 Polyclonal Antibody for your immunology and cancer research projects.
Product Name:
DLL1 Rabbit Polyclonal Antibody
SKU:
CAB14277
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-220 of human DLL1 (NP_005609.3).
Apical cell membrane, Cell junction, Membrane raft, Single-pass type I membrane protein, adherens junction.
Calculated MW:
78kDa
Observed MW:
78kDa
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.
Purification Method:
Affinity purification
Gene ID:
28514
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using DLL1 Rabbit pAb (CAB14277) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
