The DLK1 Polyclonal Antibody (CAB2715) is a versatile tool for researchers investigating the role of DLK1, a key regulator of cell differentiation and development. This antibody, generated in rabbits, is highly specific and reacts strongly with human samples, making it ideal for use in a variety of applications, including Western blot analysis. By targeting the DLK1 protein, this antibody allows for precise detection and analysis in a range of cell types, offering valuable insights into developmental processes and disease mechanisms.DLK1, also known as Delta-like 1 homolog, plays a crucial role in regulating cell fate decisions and tissue growth, making it an important target for studies in developmental biology and regenerative medicine.
Its involvement in various signaling pathways and developmental processes underscores its significance in understanding organogenesis and tissue regeneration. The DLK1 Polyclonal Antibody provides researchers with a powerful tool to explore the function of DLK1 in different biological contexts, offering new opportunities for groundbreaking discoveries in the fields of stem cell biology and tissue engineering.
Product Name:
DLK1 Rabbit Polyclonal Antibody
SKU:
CAB2715
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human DLK1 (P80370).
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
Purification Method:
Affinity purification
Gene ID:
8788
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DLK1 Rabbit pAb (CAB2715) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 30s.
