DLK1 Rabbit Polyclonal Antibody (CAB2715)
- SKU:
- CAB2715
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DLK1 Rabbit Polyclonal Antibody |
SKU: | CAB2715 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human DLK1 (P80370). |
Sequence: | AECF PACN PQNG FCED DNVC RCQP GWQG PLCD QCVT SPGC LHGL CGEP GQCI CTDG WDGE LCDR DVRA CSSA PCAN NRTC VSLD DGLY ECSC APGY SGKD CQKK DGPC VING SPCQ HGGT CVDD EGRA SHAS CLCP PGFS GNFC EIVA NSCT PNPC ENDG VCTD IGGD FRCR CPAG FIDK TCSR PVTN CASS PCQN GGTC LQHT QVSY ECLC KPEF TGLT CVKK RALS PQQV TRLP SGYG LAYR LTPG VHEL PVQQ PEHR ILKV SMKE LNKK TPLL TEGQ |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; DLK1 |
Positive Sample: | K-562,HepG2,MCF7,SW620,Mouse liver,Mouse kidney,Mouse heart,Rat liver,K-562,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 41kDa |
Observed MW: | 41kDa/ |
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
Purification Method: | Affinity purification |
Gene ID: | 8788 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |