The DLGAP2 Polyclonal Antibody (CAB13818) is a vital tool for researchers studying DLGAP2, a protein involved in synaptic function and neuronal signaling. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to DLGAP2, this antibody enables precise detection and analysis of the protein in various cell types, making it an essential tool for studies in neuroscience and neurobiology.DLGAP2, also known as PSD-93, is a scaffolding protein that plays a crucial role in organizing and stabilizing signaling complexes at excitatory synapses.
Its importance in synaptic transmission and plasticity makes it a key target for research into neurological disorders such as Alzheimer's disease, schizophrenia, and autism spectrum disorders. Investigating the function of DLGAP2 is vital for gaining insights into the underlying mechanisms of these conditions and potentially developing new therapeutic interventions.
Product Name:
DLGAP2 Rabbit Polyclonal Antibody
SKU:
CAB13818
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human DLGAP2 (NP_004736.2).
The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
9228
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DLGAP2 Rabbit pAb (CAB13818) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
