The DLG4 Polyclonal Antibody (CAB7889) is a valuable tool for researchers studying DLG4, a key protein involved in synaptic function and plasticity. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to DLG4, the antibody enables precise detection and analysis of this important protein in various cell types, making it ideal for studies in neuroscience and neurodegenerative diseases.DLG4, also known as PSD95, is a scaffolding protein that plays a crucial role in organizing and stabilizing synaptic connections in the brain.
Its involvement in synaptic plasticity and neuronal signaling makes it a promising target for research on conditions such as Alzheimer's disease, schizophrenia, and autism spectrum disorders. Understanding the function of DLG4 is essential for developing therapies that target synaptic dysfunction and cognitive impairment in these neurological disorders.
Product Name:
PSD95 Rabbit Polyclonal Antibody
SKU:
CAB7889
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PSD95 (NP_001308004.1).
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1742
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PSD95 Rabbit pAb (CAB7889) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
