The DLG3 Polyclonal Antibody (CAB16831) is a research tool specifically designed for studies involving DLG3, a protein known to play a role in synaptic function and neurological disorders. This rabbit-raised antibody is highly reactive with human samples and has been validated for use in various applications, including Western blotting. By binding to the DLG3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a valuable tool for research in neuroscience and neurology.DLG3, also known as SAP102, is a member of the membrane-associated guanylate kinase (MAGUK) family and is involved in the organization of synaptic membranes and signaling complexes.
Dysregulation of DLG3 has been implicated in neurological conditions such as autism, schizophrenia, and intellectual disabilities. Research into the function and regulation of DLG3 is crucial for understanding the molecular mechanisms underlying these disorders and developing targeted therapies. The DLG3 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of DLG3 in synaptic function and neurological disorders.
Product Name:
DLG3 Rabbit Polyclonal Antibody
SKU:
CAB16831
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 464-817 of human DLG3 (NP_066943.2).
This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
1741
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DLG3 pAb (CAB16831) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
