The DLG1 Polyclonal Antibody (CAB8542) is a valuable tool for researchers studying the DLG1 protein, a key player in cell adhesion and signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blotting applications. By specifically binding to the DLG1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component for investigations in cell biology and cancer research.DLG1, also known as discs large homolog 1, plays a crucial role in maintaining cell structure and function by mediating interactions between proteins involved in cell adhesion and signaling.
Its involvement in important cellular processes makes it a promising target for research on diseases such as cancer and neurological disorders. Understanding the function of DLG1 is essential for developing new therapies that target signaling pathways mediated by this protein, offering exciting possibilities for advancing treatment options in various disease contexts.
Product Name:
DLG1 Rabbit Polyclonal Antibody
SKU:
CAB8542
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human DLG1 (NP_004078.2).
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. A multitude of transcript variants deriving from alternative splicing and the use of multiple alternate promoter have been observed, including some splice variants that may be specific to brain and other tissues. An upstream uORF may regulate translation at some splice variants of this gene.
Purification Method:
Affinity purification
Gene ID:
1739
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DLG1 antibody (CAB8542) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
