The DLDH Rabbit Monoclonal Antibody (CAB5220) is a cutting-edge tool for researchers studying lactate dehydrogenase (DLDH), a key enzyme involved in cellular metabolism and energy production. This antibody, developed using advanced rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting DLDH in various biological samples.DLDH plays a crucial role in the conversion of lactate to pyruvate, which is essential for ATP production and maintaining cellular functions. Dysregulation of DLDH activity has been linked to various diseases, including cancer, metabolic disorders, and neurodegenerative conditions. By targeting DLDH, researchers can gain insights into metabolic processes and develop new therapeutic strategies for treating these diseases.
The DLDH Rabbit Monoclonal Antibody is validated for use in techniques such as Western blotting, immunohistochemistry, and immunofluorescence, offering versatility for different experimental approaches. Its high affinity for DLDH ensures reliable and reproducible results, making it an indispensable tool for studies in molecular biology, biochemistry, and disease pathology.Overall, the DLDH Rabbit Monoclonal Antibody (CAB5220) is a valuable asset for researchers seeking to explore the role of DLDH in cellular metabolism and disease pathogenesis. Its specificity, sensitivity, and reliability make it a trusted reagent for advancing scientific knowledge and driving innovation in biomedical research.
Product Name:
DLDH/DLD Rabbit Monoclonal Antibody
SKU:
CAB5220
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 401-500 of human DLDH/DLD (P09622).
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1738
Clone Number:
ARC1224
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DLDH/DLD Rabbit mAb (CAB5220) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
