DLDH/DLD Rabbit Polyclonal Antibody (CAB5403)
- SKU:
- CAB5403
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DLDH/DLD Rabbit Polyclonal Antibody |
SKU: | CAB5403 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human DLDH/DLDH/DLDH/DLD (NP_000099.2). |
Sequence: | ADQP IDAD VTVI GSGP GGYV AAIK AAQL GFKT VCIE KNET LGGT CLNV GCIP SKAL LNNS HYYH MAHG KDFA SRGI EMSE VRLN LDKM MEQK STAV KALT GGIA HLFK QNKV VHVN GYGK ITGK NQVT ATKA DGGT QVID TKNI LIAT GSEV TPFP GITI DEDT IVSS TGAL SLKK VPEK MVVI GAGV IGVE LGSV WQRL GADV TAVE FLGH VGGV GIDM EISK NFQR ILQK QGFK FKLN TKVT GATK KSDG KIDV SIEA ASGG K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:500 |
Synonyms: | E3; LAD; DLDD; DLDH; GCSL; PHE3; OGDC-E3; DLDH/DLD |
Positive Sample: | MCF7,BT-474,K-562,293T,Mouse kidney,Mouse skeletal muscle,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 54kDa |
Observed MW: | 55kDa |
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1738 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |