DLC1 Rabbit Polyclonal Antibody (CAB1921)
- SKU:
- CAB1921
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DLC1 Rabbit Polyclonal Antibody |
SKU: | CAB1921 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human DLC1 (NP_079043.3). |
Sequence: | DAPK VNAV DTLN VKDI APEK QLLN SAVI AQQR RKPD PPKD ENER STCN VVQN EFLD TPCT NRGL PLLK TDFG SCLL QPPS CPNG MSAE NGLE KSGF SQHQ NKSP PKVK AEDG MQCL QLKE TLAT QEPT DNQV RLRK RKEI REDR DRAR LDSM VLLI MKLD QLDQ DIEN ALST SSSP SGTP TNLR RHVP DLES GSES GADT ISVN QTRV NLSS DTES TDLP SSTP VANS GTKP KTTA IQGI SEKE KAGK LTFW FCFL ANLF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HP; ARHGAP7; STARD12; p122-RhoGAP; DLC1 |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, Membrane, Peripheral membrane protein, focal adhesion. |
Calculated MW: | 171kDa |
Observed MW: | 171kDa |
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10395 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |